Following the acquisition of GEA Pharmaceuticals A/S in June 2007, PharmaZell can now offer the
development of finished dosage forms as well. Under the new company structure PharmaZell provides
a fully integrated approach in drug product development - from API to marketing authorisation - covering:
• Drug Product Development
• Analytical Development
• Bioequivalence Studies
• API R&D Laboratory
• API Multipurpose Production
• Regulatory Affairs
• Intellectual Property
• Project Management
• QA/QC
Drug product development work at PharmaZell focuses on solid dosage forms - with particular expertise in the
field of functional coatings and pellets - and comprises:
• Formulation and Process Development
• Manufacture of Clinical Trial Batches
• Scale up/Tech. Transfer to Costumer Sites
• Development and Production Support
The analytical development department is equipped with the following instruments and technologies:
• Chromatography (HPLC, GC, IC)
• Dissolution
• Titration
• Spectrometry (UV, IR)
• All Pharmacopoeia Instrumentation in order to enable and establish
• Specifications (APIs and Drug Products)
• Method Development/Validation/Transfer
• Stability Studies
While clinical studies as such are typically performed by contract research organisations, PharmaZell
offers the following services - utilizing HPLC-MS - to support following Phase I related tasks:
• Bioequivalence Studies
• Bioanalytics, Method Development/Validation
• Biometry
Regulatory affairs is represented in the development teams to ensure competent and timely input about
latest regulatory requirements and authority practices.
Regulatory affairs provides services within:
• Preparation and Assessment of Regulatory Documentation
including Drug Master Files
• Adjustment of Regulatory Documentation from Non-EU to
EU Requirements or vice versa
• Regulatory Procedures
• Regulatory Strategies



